Would creating your own PG solution of Etiz directly from the powdered hcl form in a 1ml/2mg concentration, then diluting .5ml of your PG etiz mix into 5ml or 10ml of warm/hot dH2O, shaken up, sucked up with oral syringe, and plugged?.. Etiz being soluble in PG, and PG being soluble in water this would work, no?
I'm not asking for higher bioavailability over oral, but what about a faster onset? Sometimes extreme anxiety/panic attacks can be so debilitating, that 30 minutes to wait for the first signs of anxiolytic effect is pure torture let alone the full 45-60 minutes to completely erase the anxiety attack.. Yes my alprazolam script takes forever. My PG/Etiz mix's onset is about the same onset taken orally, under the tongue as my alprazolam.
Just cutting this onset time by a third or better would be a godsend for those us who get hit with a panic/anxiety attack at such random times. (And no I refuse to try any of the SSRI's and similar treatments as I do not enjoy the blunt in emotions it gives me). Treating my acute rare episodes via these types of compounds seems to be the best treatment option for me, and my dr agreed after exploring several other options with me on mini trials. None worked, except the alprazolam.
Perhaps a faster onset could be used in a harm reduction scenario as well. We hear all the time of some careless kids taking monster 160mg+ doses of potent RC stimulants that are intended to be dosed in the 5-20mg range, that naive and carelessness could cause extremely distressing effects on the CNS and PNS such as tachycardia, and/or hypertension, and left untreated could lead to a stroke or heart failure. Of course calling an ambulance is the best option here. The health professionals will treat the symptomatic issues from stimulant abuse, usually with something like Ativan or similar depending.... It could help to have an ROA for these types of sedatives that are on the RC market that can speed up absorption rates to combat issues like these, as it could take 10, 15, 20 or even 40 minutes for EMT's to arrive depending how far away from a city/town these hypothetical kids were while "researching".