Yeah, i'm definitely prone to (or wary of) developing headaches on phen psychs.
It seems pretty common with my experience with a few 2C-x drugs, and last weekend i got a pounding headache on an otherwise smooth and pleasant mescaline trip.
At the time I blamed the stuffy, smoky room i was in - which might have been the cause - but it seemed like i was maybe more sensitive to the headache from the mescaline.
Fortunately, once i left that house and took some paracetamol, the headache went away and i felt fine - but as above, i felt compelled to drink a lot of water to remain hydrated, and it felt like that helped a lot.
I love mescaline, but am much less enthusiastic about phenethylamine psychedelics than i am tryptamines; i don't feel like they play well with me - and i know that some people are the opposite.