Other Mushroom Alkaloids Tested

[Pfafffed]

Scientists Synthesize and Test the Magic Mushroom Compounds Baeocystin, Norbaeocystin, Norpsilocin, and Aeruginascin

This work is a giant step forward for psychedelic research.

psychedelicreview.com

So, if we believe Gartz (1995), then baeocystin can potentially occur at concentrations 1/3 that of psilocybin in dried mushrooms.

Baeocystin is dephosphorylated into norpsilocin in the body.

If this new research is correct, then the use of a RIMA like syrian rue might prevent the breakdown of some of the norpsilocin. Norpsilocin is almost a full agonist at 5-HT2a, unlike psilocin. It's possible then I guess that in samples with a high baeocystin content, the molecule might influence the drug experience if an MAOi were taken.

We know that RIMAs make 4-subbed tryptamines stronger when taken alone (don't we?) so who knows what effect if any this really has.

 

[Xorkoth]

Interesting. I've long wondered if the other alkaloids in mushrooms do affect the experience in some way, and whether there is any method of ingesting them that would produce worthwhile effects.

 

[TripSitterNZ]

i know our subs in nz have high baeocystin i get wood lovers paralysis on higher doses and numbing of my entire body while extremely coloured OEVs. I could test out their effects this season with a Maoi in the name of science.

 

[Pfafffed]

Or you could just eat some more of those sweet, sweet Weraroa novae-zelandiae ;-)

Creepy looking little buggers

 

[Blowmonkey]

baeocystin alone would likely not induce 5-HT2A receptor-mediated psychoactive effects in vivo.

Oh, I always assumed that'd be the one most likey to lead to the variance in effects reported amongst all the different species and strains, but it doesn't do anything? I didn't expect that at all.

I just searched and am going to spam your topic by answering my own question of what else it could be.
Simultaneous Production of Psilocybin and a Cocktail of β‐Carboline Monoamine Oxidase Inhibitors in “Magic” Mushrooms

 

[Xorkoth]

I have a very hard time believing it does nothing at all.