Strips and films for buprenorphine and fentanyl and so forth -- is the idea to make an alternative transmucousal delivery system for the medication with more surface area than a tablet, lozenge, or lozenge-on-a-stick and therefore delivers the drug all at once , all other things being equal?
The Fentora fentanyl buccal tablet which fizzes was a great idea for another delivery system. Any time you add bubbles it will cause faster absorption -- like way back when breaking Alka-Selzer Cold Medicine into pieces, putting them betwixt my cheek and jaw, and squirting Codiclear or Numorphan or Dilaudid HP on them so it all went through the lining of my mouth faster and hit harder. I actually did that with the young lady who first taught me about potentiating opioids with antihistamines; she is a saint. . . . If you have your significant other or another squeeze with you, it is possible to make all that into the equivalent of a "snowball" so that you both can get some, as in the term "Snowball Queen"* which one encounters in
Little Red Riding Hood . . .
en.wikipedia.org
---
* I cannot believe Wikipedia is the only place with an accurate definition for this, quality control is worse than one may think. Why? I guess the same thing that let the air out of three of the tyres on Usenet. People like Milgram found who shouldn't have any kind of power getting it then trying to close the drawbridge. It seems that the way the old and/or noisy WP folks mob contributors who are or appear to be newer, delete things with reckless abandon, and hammer the newer contributors and those with other ideas to freeze them out does most of this. Basically bush league power-tripping. I have seen the mandarins, self-appointed, I guess, over there crow about how distrustful and misanthropic they are as if it makes them better contributors, and they seem to traffic in truly bizarre and ostensibly self-serving ideas like "hidden vandalism" (the latter word being a shibboleth and catch-all for anything they don't like, sort of like Joe Mc Carthy and Communist) and even stranger ones still . . . It all makes for mediocre content which diminishes further over time . . . I did enough reading there to know not even to try to contribute, and my organisation and I formally have had to follow a number of wise professors we know and declare that WP is neither an acceptable source nor destination for any of our work (the pharmacology and medical articles really have taken a hit over the years, some of it like the former navigation box for opioids being subjected to just wanton destruction for no visible reason) but here we go.
Needless to say there is no real WP discussion of the reality behind the fake Opioid Cri$i$ and so on, but what I saw happen to the article about the abominations of 11. September 2001 was the worst -- long about 2008 there was perfectly well-sourced information about all aspects of it, and the article as a whole could serve as a roadmap and preliminary bibliography for someone wanting to do a more in-depth investigation which ties together the known information and a lot of miscellaneous strange things. The roadmap/bibliography use for WP was my original hope for it, and it is next to useless for most topics now.
