Yes, but tapering to reduce your dose will take longer.
Frankly just taking a 48hr break will begin to significantly lower your tolerance. Four days it will be much lower. A week and it will be nearly baseline. It will build up again pretty fast, so dosing as low as is practical and being really consistent with using them a lowish dose of a moderate to long acting NMDA agonist (like 60-90mg DXM polistyrex) will be important if you want to prevent your tolerance from rising again to fast.
With opioid use, when there wasn't as issue with scarcity I tended to find a dose I liked but was very careful about my propensity toward compulsive use. stick to it with regularity. Frankly once I found that place tolerance wasn't a big issues, as I got what I needed out of it.
When you are taking you opioid taking it once a day (no more than twice a day) as consistently as possible it will take significantly longer for tolerance to develop than if you were to take a normal dose one day and a huge dose another.