I used to get very irritable with certain opiates, usually when the rush and the best part of the high would be on its way out.. One day me and a few friends did some opana 40s back in the day, the OG yellow octagons, not the new antiabuse ones, and we all sniffed about 10-20mg and were feeling great, then all of us simultaneously got out of the car and threw up, literally all 3 of us at the same time, lol. and this particular day, I don't know what it was, but we all started fighting about the stupidest shit! I believe we went to Wal-Mart afterwards, and just fucked around, don't even know why we went there, then all of us, including myself just became very irritable.. and just mean! it was odd.. I think maybe Ksa has a point, its best to just chill after doing opiates, and usually I would, just chill, nod out, and love every fucking second of it! Especially with oxymorphone(opana), that is and always will be my favorite opiate, but it is the only one that REALLY makes me moody when it starts to wear off, while something like oxycodone, wouldn't really make me AS moody.. as long as I had enough to get by.. I think it was because of how fucking incredible the rush/high of opana when done intranasal or IV is.. then when it wears off, its like fml, this sucks... idk, but I have always had better experiences with opiates just by myself, or maybe with one other person, and me and that person usually didn't say more than 3 words to one another while nodding out, comatose, and in pure bliss from the opiate euphoria.. Opiates/opioids are definitely not party drugs!