So I live in California and have gotten weed from several sources, including dispensaries. The friends I've done it with range from occasional smokers to full blown stoners, so I trust what they say. I used to do mushrooms a lot, and have recently been doing MDMA a bit, but usually with small doses and in moderation. I don't take any medication so I doubt anything is really affecting my brain that way. Maybe I am just not doing enough, and then unknowingly taking way too much when I have tried higher doses which caused me to green out, but I thought my doses were measured out right. Anyway, thanks for the input.
It is very possible you have an issue with the cannabinoids in the cannabis and your receptors. Now the cannabinoid system is affected by opioids slightly and drugs such as MDMA have a role as do most mood altering drugs of those sorts since the endocannabinoid system is extensively connected. All I could personally suggest is trying to make sure your doing it right smoking it right holding it in getting decent stuff even if this means literally testing your weed for thc.
As said above Synthetics are a real possibility and its still debated but if you have interacted with a synthetic in the past the idea is it could have affected/damaged your system, other possibilities I could think of would include:
Clinical endocannabinoid deficiency, otherwise known as CECD, describes a physiological state where the body produces low levels of endocannabinoids. These molecules serve as chemical messengers and help many other bodily systems function, from the digestive system to the nervous system. Each individual has their own “endocannabinoid tone”, or the amount of endocannabinoids that their body produces.
Cannabinoids such as THC share a trait with endocannabinoids, allowing them to bind to the same receptors. THC may only return a person's endocannabinoid tone to a baseline level if they experience endocannabinoid deficiency, meaning it might take a lot more cannabis for these individuals to start feeling the psychotropic effects. This is just conjecture, though.
Furthermore you not ever having been a smoker and not describing negative symptoms or affects from this makes me think receptor downregulation is not at play here.
"
CB1 receptor downregulation produces a condition called endocannabinoid dysregulation. With a single use of cannabis, endocannabinoid dysregulation negatively impacts the performance of highly complex tasks for at least 24 hours."
Sorry if I couldn't be of more help, if I couldn't feel my weed fuck id be mad.
