Are you talking about short term (ie the night you roll and are trying to sleep) or long term (symptoms stemming from abuse)?
For short term, benzos and/or antipsychotics are the best along with marijuana. I’ll usually take something like 1mg xanax or 10-20mg ambien along with 25-50mg seroquel and smoke some. I’m almost always using LSD with MDMA so if you’re just using MDA/MDMA then you won’t need that much.
As far as neurochemical support, I also include... High quality fish oil, alpha lipoid acid, vitamin c, NAC, CBD, metformin, and piracetam typically the night of.
As far as long term, lots of threads on this. Maintaining a healthy diet (whole foods, no processed/prepackaged, fruits, veggies, healthy fats and lots of protein) and getting regular moderate-high intensity exercise are the best things you can do.