I understand that Loperamide (Immodium) is dangerous in high doses. However, it seems that if we are being realistic, it is still a major go-to for folks who find themselves suddenly without Opioids. It's not a good thing, but I think if people are going to use it, it's best to keep the dosage as low as possible. Keep in mind that the damage caused by this stuff might not be readily apparent.
It is pretty difficult to make responsible decisions when you are sick and you have an agent at-hand that can relieve your symptoms. My advice would be to not buy the wholesale size bottle of Loperamide so that you have some semblance of control on the dosage. I'm speaking from experience on this one.