I take Adderall for a little energy because I have Fibromyalgia and chronic fatigue...ive never had any issues until about 4 weeks ago I started taking LDN (low dose naltrexone) it was only 2mg...it is used in low doses to help with chronic pain...well I noticed that when I took it I couldn't feel the effects of my Adderall...i only took the naltrexone for 2 days and now it's like my receptors are permenetly blocked! 4 weeks later and I still can't feel the Adderall. And I know this sounds weird bc naltrexone only blocks opioid receptors but it obviously has blocked something else...please believe me...im not crazy!