cryptix420
Bluelighter
- Joined
- Jul 25, 2010
- Messages
- 1,419
Howdy all,
I've been intensely fascinated by this [incredibly affordable and accessible at virtually every health foods store] supplement called N-acetyl-cysteine, or NAC. I used it years ago when I heard it was a great think to take before drinking alcohol to prevent a hangover (it is true), but never knew it had such a plethora of other impressive (and relevant to me) benefits. Although, there are probably certain entities *coughbigpharmacough* that would rather people didn't know about all this.
The WHO requires that any hospital or similar institution keep NAC on hand in case of alcohol or acetaminophen/paracetamol (Tylenol) poisoning. When overdosing on acetaminophen, the toxic metabolites consume all of the liver's glutathione (one of the most important endogenous antioxidants) and then these by-products build up and cause permanent damage to liver cells. NAC is so magical because it is a direct precursor (or very close to one) to glutathione.
Actually, don't quote me on that - I know that NAC donates cysteine (a sulfur containing amino acid) to the body, and it may be that cysteine is needed to produce glutathione, but it serves other functions as well.
I've come across some studies lately that say some very, very interesting things about NAC, such as that it treats:
Here's a couple of those studies:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044191/
https://www.ncbi.nlm.nih.gov/pubmed/29126981
But what REALLY caught my attention, is that supposedly NAC can prevent dopamine loss related to meth/amphetamines. This is huge!! (if true)
https://www.hindawi.com/journals/pd/2012/424285/
We all know it's usually pointless to tell someone to 'stop taking drugs' even if it's ruining their health and life. But, if someone in that situation could simply pop a pill, with benefits this enormous....I mean, let's spread the word eh?
It just seems the implications of this substance are huge for many, many people - especially in our community here at Bluelight. Personally, I have noticed a sharp decline in paranoid thoughts since taking this stuff. From my research, it appeared I was dosing too low in the past to gain these benefits. Upwards of 2g a day seems to be a good place to get started.
While I couldn't quite gain an understanding from reading the research, it also seems that NAC has beneficial effects on NMDA receptors and glutamate activity - which sounds like it good be a very good thing for anyone who has gone a bit too far with dissociatives.
P.S. - Just in case anybody reading this decides to try NAC to prevent alcohol hangovers, I remember reading somewhere that taking NAC before drinking alcohol drastically reduced toxicity, but taking NAC after beginning alcohol consumption led to increased toxicity. I can't say for sure it's true, but just wanted to put that out there.
Much Love, Bluelighters.
I've been intensely fascinated by this [incredibly affordable and accessible at virtually every health foods store] supplement called N-acetyl-cysteine, or NAC. I used it years ago when I heard it was a great think to take before drinking alcohol to prevent a hangover (it is true), but never knew it had such a plethora of other impressive (and relevant to me) benefits. Although, there are probably certain entities *coughbigpharmacough* that would rather people didn't know about all this.
The WHO requires that any hospital or similar institution keep NAC on hand in case of alcohol or acetaminophen/paracetamol (Tylenol) poisoning. When overdosing on acetaminophen, the toxic metabolites consume all of the liver's glutathione (one of the most important endogenous antioxidants) and then these by-products build up and cause permanent damage to liver cells. NAC is so magical because it is a direct precursor (or very close to one) to glutathione.
Actually, don't quote me on that - I know that NAC donates cysteine (a sulfur containing amino acid) to the body, and it may be that cysteine is needed to produce glutathione, but it serves other functions as well.
I've come across some studies lately that say some very, very interesting things about NAC, such as that it treats:
- Major depressive disorder
- Bipolar disorder
- Drug addiction
- Obsessive-compulsive disorder
- Autism
- Schizophrenia
- Alzheimer's disease
- Certain forms of epilepsy
Here's a couple of those studies:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044191/
https://www.ncbi.nlm.nih.gov/pubmed/29126981
But what REALLY caught my attention, is that supposedly NAC can prevent dopamine loss related to meth/amphetamines. This is huge!! (if true)
https://www.hindawi.com/journals/pd/2012/424285/
We all know it's usually pointless to tell someone to 'stop taking drugs' even if it's ruining their health and life. But, if someone in that situation could simply pop a pill, with benefits this enormous....I mean, let's spread the word eh?
It just seems the implications of this substance are huge for many, many people - especially in our community here at Bluelight. Personally, I have noticed a sharp decline in paranoid thoughts since taking this stuff. From my research, it appeared I was dosing too low in the past to gain these benefits. Upwards of 2g a day seems to be a good place to get started.
While I couldn't quite gain an understanding from reading the research, it also seems that NAC has beneficial effects on NMDA receptors and glutamate activity - which sounds like it good be a very good thing for anyone who has gone a bit too far with dissociatives.
P.S. - Just in case anybody reading this decides to try NAC to prevent alcohol hangovers, I remember reading somewhere that taking NAC before drinking alcohol drastically reduced toxicity, but taking NAC after beginning alcohol consumption led to increased toxicity. I can't say for sure it's true, but just wanted to put that out there.
Much Love, Bluelighters.
Last edited: