Diacetylmorphine metabolizes to morphine and 6-MAM, of which the latter does hit on other receptors not normally touched by morphine alone.
I’ve had grams upon grams of morphine sulfate as well as lots of very pure Diacetylmorphine, I prefer the Diacetylmorphine.
With heroin there’s more euphoria, it’s more energetic, and of course it hits quicker. There’s less histamine release so you don’t give yourself away.
For me back in th day it wasn’t the tracks that gave me away, it was the red flushed face with scratch marks all over it and pinned eyes. Avoiding that red face was key.
I felt like heroin even had less itch than Oxycodone too. But maybe it was just tolerance related.
“There is also evidence that 6-MAM binds to a subtype of μ-opioid receptors that are also activated by the morphine metabolite morphine-6β-glucuronide but not morphine itself.[77] The third subtype of third opioid type is the mu-3 receptor, which may be a commonality to other six-position monoesters of morphine. The contribution of these receptors to the overall pharmacology of heroin remains unknown”
-GC
I’ve had grams upon grams of morphine sulfate as well as lots of very pure Diacetylmorphine, I prefer the Diacetylmorphine.
With heroin there’s more euphoria, it’s more energetic, and of course it hits quicker. There’s less histamine release so you don’t give yourself away.
For me back in th day it wasn’t the tracks that gave me away, it was the red flushed face with scratch marks all over it and pinned eyes. Avoiding that red face was key.
I felt like heroin even had less itch than Oxycodone too. But maybe it was just tolerance related.
“There is also evidence that 6-MAM binds to a subtype of μ-opioid receptors that are also activated by the morphine metabolite morphine-6β-glucuronide but not morphine itself.[77] The third subtype of third opioid type is the mu-3 receptor, which may be a commonality to other six-position monoesters of morphine. The contribution of these receptors to the overall pharmacology of heroin remains unknown”
-GC