Interesting stuff, seriously. You've given me a lot to consider/try. Again, thank you, I appreciate all the effort you've put in.
Funnily enough, I am sitting on some psilocybin (I have yet to try any mushroom), waiting for the right time. I'm currently going through exam period at university, so I can't be too much of a guinea pig until a week's time haha. I'm actually so excited just to see how my tremors react to it. I actually did some research after I read your post, and quite a few people have had their tremors completely relieved while tripping (exciting!).
There are quite a few specific things that may or may not be beneficial to determining the issue that I would like to mention.
Firstly, LSD makes my tremors worse. To my understanding, it works similarly to mushrooms in that it 'mimics' (in the sense that it is mistaken by the brain) serotonin and also agonises 5-HT2A. However, LSD is quite stimulating, so I wouldn't be surprised if it's just because of that. I'm never 'relaxed' on LSD, though apparently some people are. Thoughts on this?
Other psychedelics I have experience with is 2C-E (three times: once intranasal, twice oral) and 2C-I (once, oral), both of which made them worse (though 2C-I was incredibly physically stimulating, so no surprise). The reason I point this out is because whenever I have smoked weed in conjunction with MDMA or 2C-E, during the comedown, I am at my absolute worst, and it's not just in my hands, my legs are shaking off and on and feel extremely weak (it is quite a mission to even walk), as well as the rest of my body. This happened during the peek of 2C-E also, but I have only ever noticed this happening with weed in conjunction (this includes MDMA). My first time with 2C-E (intranasal) was nowhere near as intense as oral, and I didn't smoke weed that first time: no convulsions. I'm not sure what part weed plays in this, or if it's just a coincidence that I happen to be ingesting both weed and some other substance that alone is causing the convulsions, and just didn't happen those times, which I suppose is entirely possible.
I also get a lot of twitches after smoking weed, though research says this is pretty normal for some, especially when you're really high, but it doesn't take too much weed for it to happen to me, and I believe I get it worse than most, but I can see it as just working with the tremors, hence making it noticeably worse.
I'll buy some DXM to try. I do have diphenhydramine currently (non-drowsy, double mucus relief, if it makes any difference -- would the drowsy version be more beneficial for testing? I imagine not, since we're talking about the active ingredient here.) I'm ordering some 5-HTP right after this post to try.
Clonidine and Citalopram seem interesting. I might be able to try them if all else fails (beginning with Clonidine perhaps), anything that potentially solves/determines the issue is worth a try. It seems very similar to Propranolol in terms of treating hypertension, but Clonidine is also used for ADHD? Interesting. I'm a little curious, how might it be more effective in comparison to Propranolol?
I do have experience with opiates: oxycodone and heroin. I'm pretty certain my tremors worsen, but it can be difficult to pay attention to things like tremors while under the influence. I could try and see how I react, just to be sure of the result.
I'm happy to share anything if it means I can potentially be rid of these tremors. I have no other neurological type problems apart from migraines and tremors, as far as I'm aware. I have had a sleep-deprived electrocardiogram, to determine why I was getting the awful pain in my head. I couldn't sleep during the test, but they said it didn't matter too much. They said it was normal. I'm unsure what information it could lead to apart from showing that I don't experience seizures. It ended up being formally diagnosed as a recurring icepick migraine.
Now, I am unsure of the relevancy, so I'm just going to dish out some other medical facts that might be helpful.
Firstly, there is quite a bit of mental illness on both sides of my family tree, and also my immediate family. My mother has bipolar, along with a plethora of other things (Addison's disease, leukaemia, and a lot of other things I'm not too sure of). Both of my siblings (twin males) have Asbergers (my only siblings), one also has very mild Cerebral Palsy. On my father's side, there is history of mental illness and heart disease, but I'm unsure of the specifics. Though, I don't believe my father himself suffers from mental illness.
I have always been curious about whether I have Asbergers or anything of the sort given my history. I can relate to some symptoms that I have read (but perhaps that's just my personality), but a lot of the autistic traits I see in most such as lack of motivation and being easily distracted isn't me, I'm quite focused and motivated in general. I am surrounded by four people with forms of autism (two friends), and I see similarities between them that I don't think I have (things like sub-genres in music, even). Everyone is different, though.
Moving on, I've always had a hard time getting to sleep (once I'm asleep, I'm fine), so I would say perhaps insomnia could be included. Not overly interesting.
However, I do have what I've been told is quite a rare condition: "monocular vertical diplopia," says a neuro-ophthalmologist, and there is no explanation for it. Eyes are supposedly fine, as is my brain. I noticed this when I began experiencing migraines for the first time (mid-2012). It still persists and has not gotten any better, and the doctors completely disregarded it. I see a transparent version of the 'object' above it. For example, white lines on the road have a hovering line above it (as if it's floating on air). I don't know if I've always had it and just not noticed, because it doesn't bother me really, it's mild, but not overly subtle.
The reason I haven't moved this to PM yet is because it may be beneficial for someone with the same problem, but I'm happy to move it over there if it's more convenient. I could always append to this thread later when/if the issue is solved. I'll definitely keep you updated with what I have tried and how I have reacted, if you like and still hold interest.
I apologise if this is a hassle to read, I'm trying to make it easier for the both of us by being as explicit as I can.
Thanks again! Feel free to ask me anything.