I thought I would post this but it is quite anecdotal with only personal experiences. I was suffering from my latest set of migraines last year. I was having one to two a week. Full aura and my day being a write off, many times at work at a hospital . I did LSD for the first time last summer and have fallen in love with it. The best side effect has been I have yet to suffer a migraine in 10 months. I believe this is no coincidence. My brain feels different since I dropped and I no longer feel on the verge of a migraine. Those who suffer know this feeling. I am a medical professional and have had access to all sorts of treatments, the closest to resolving symptoms being aminophylline IV 100mg over 20 min. That med would do nothing in regards to prophylaxis. Just thought I would post this as I believe LSD has real medical benefit in this case. I know LSD was found in research for migraine medication. Hofmann was onto something.