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Pharmacology Learn from Viminol

This thread contains discussion about a Pharmacology-related topic

AlsoTapered

Bluelighter
Joined
Apr 1, 2023
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There are 6 isomers if viminol. 4 are inactive, one is an agonist, the other an antagonist. It's because it forces the H: into the agonist conformation. In some certain research, N-n-butyl was tested but N-(S) s-butane will NOT allow the H to enter the antagonist conformation.

I've only ever seen this trick in Viminol but antagonists and mixed agonists are also possible. In a lot of research, the N-n-butylamine example is
used and it would be interesting to see which examples need the (S) s-butylsmine, are agonists, antagonists or don't care.

A fascinating way to make a SAFE product.
 
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