@twelvefingers So you can take 15g of kratom (or how much was a single dose of yours?) without getting uncomfortable nervousness? This is my primary concern with kratom as I've read that overdose comes with anxiety, heavy tachycardia etc. but reports are conflicting here.
I don't really feel much from 5g of gold vein, which is the max recommended dose according to the headshop but I don't feel much. It has a verry subtle warmth but it might as well be placebo. So just take another 2.5g or even 5g?
Weird that a partial agonist (apparently it is one, didn't know but somebody mentioned this yesterday) does increase opioid tolerance so much, it should rather be less problematic than the full agonists like oxy, morphine etc.
Found kratom to be effective for physical withdrawal symptoms though and it seems to produce less of them by itself, at least much less diarrhea, but some runny nose and sweating. Would be great if it didn't cause so much depression and anxiety like morphine does.
Also interesting that kratom is an alpha2-adrenergic agonist which are autoreceptors, thus actually decrease the output of norepinephrine but still seems to be somewhat stimulating in nature.