I do it all the time.With large ammounts of both.I do,however have a high tolerance for both.In fact,before quitting H,It was my favorite cocktail,with liquor added to the mix.Don't get me wrong.I'm in no way encouraging this potentially deadly mixture.As far assume your safety goes,it depends on your tolerance to each drug.Start with a sensible ammount and work up to where you want to be.Above all,be sensible and safe.I wasn't because I was at a point in my. life where I didn't give a shit.Just trying to relate my personal experience and advise caution.Be safe and happy partying.