I think giving people practical advice for what they can do to protect their brain from neurotoxicity, their heart from cardiotoxicity, and reduce their comedowns from amphetamine type stimulants would be really helpful.
Tyrosine is magic for methamphetamine comedowns. 5HTP works pretty well for ecstasy comedowns. Food really helps too although eating can be a struggle for amphetamine users, advice on convenient liquid foods could be helpful though.
Antioxidants are useful for reducing neurotoxicity, the ones that are best supported by animal data are alpha lipoic acid, cysteine, vitamin C, vitamin E, carnitine and selenium.
Treatments to reduce the high blood pressure associated with amphetamine use could have a very significant impact on long term cardiovascular damage from amphetamine use, particularly calcium channel blockers like diltiazem and nifedipine.
Antidotes to counteract the effects of acute ecstasy overdose is an area that there really needs to be decent research done, as the current approved treatments like cyproheptadine and external cooling are pretty crap really, and from my discussions with hospital doctors they were far too scared of legal liability to risk trying out untested treatments.
The combination of prazosin and pindolol completely prevented ecstasy hyperthermia in animal models, as did carvedilol by itself, yet the official policy is that its not safe to use beta blockers in people who have taken stimulants even though this is only true for pure beta blockers used alone, while a mixed alpha / beta blocker combination can effectively treat hyperthermia and hypertension without triggering vasoconstriction.
Why are approved hospital practices and medical countermeasures for reducing the harmful side effects of amphetamine type stimulants still 10 years behind the current research in the field?