2C-E is a majestic beast. It's like it turns off my autonomy of thought, and everything is a new thing to be considered. I guess all good psychedelics do this to some extent but 2C-E does it really strongly. I am usually uneasy until the state stabilizes itself, the come-up and peak I generally feel some degree of uncomfortable and tense, and then post-peak I start to feel warm and glowy and serene, with a lot of great and deep thoughts and insights. Communication is difficult for me until post-peak. I am pretty much always left with a sense of something good having happened, with clearer thoughts on things. The visuals are very intense with full-scale perspective shifting and super clear vision and hearing, and also small-scale fractal-style patterns, very organic visuals IMO, similar to LSD or tryptamines. Best music enhancer of anything out there, and fully immersive, narrative CEVs.
On the other hand, 2C-B feels very nice the whole time (I mean I imagine the come-up would still be somewhat unpleasant if you tend to have unpleasant come-ups, personally I don't anymore and the whole thing from first alerts to the end feels pleasurable), and puts you into a happy, loving state of mind, partially empathogenic. Not too deep. Great visuals, but a "persian rug" style, colorful, vibrant crawling patternings, without the full-scale perspective shifting/waving of 2C-E. Great music enhancement with good immersive CEVs but not as much as 2C-E. 2C-B is mostly recreational for me, for a more useful/introspective trip that is similar to 2C-B otherwise, I really love 2C-C.
I think the different 2C-Xs differ from each other moreso than the different 4-substituted tryptamines do. Which is one reason why they're such cool drugs.
The 2C-Xs were the original popular research chemicals, it's a real shame that they've basically disappeared, because there are a lot of really great psychedelics in there. 2C-T-2 and 2C-T-7 are also gems.