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  • BDD Moderators: Keif’ Richards | negrogesic

If cocaine blocks reuptake of dopamine..

N

new2drugs

Bluelighter
Joined
Apr 2, 2022
Messages
714
Could you flood your brain with dopamine as you take cocaine so as to trap more?

For example....take a line, the go masterbait.

Will that trap that dopamine being released during orgasm?
 
Cocaine isn’t your typical DRI ….like Bupropion (Wellbutrin)

Cocaine is strikingly similar to Methylphenidate (Ritalin), both being classified as “Inverse Aginists” which release monoamines DAT/NET/SERT in addition to inhibiting their reuptake, resulting in Dopamine building up in the CNS

Cocaine is………………….DAT>SERT>>NET (dopamine & serotonin predominant over norepinephrine)
Methylphenidate is……….DAT>NET (3-4x more dopamine release over norepinephrine)

Methylphenidate (Ritalin) is actually nearly twice as potent as Cocaine at DAT (ED-50) effective dose to inhibit 50% of dopamine transporters DAT which is required to experience euphoric effects

That’s why they call Ritalin “Kiddy Coke” as it’s nearly identical in its MOA and given to kids with ADHD
First time trying Ritalin 20mg tablet I was euphoric & happy, robust mood-boosting properties with minimal cardiovascular negative effects such as increased HR & BP. Safer than the typical amphetamine medications, excluding Dexedrine & Desoxyn

So you wanna blast Cocaine and jerk off for maximum dopamine release lol.

Pitter padder…..

You want more pleasurable dopamine release? Take an oral Speedball lol. No, really :)

Oxycodone 10mg & Methylphenidate 20mg orally administered SUPER EUPHORIC
Cocaine & Heroin I.V. injection ……BOOM 100% Pure Ecstasy

Opioids are SUPER euphoric & pleasurable…adding a dopaminergic stimulant practically Triples the Euphoric Pleasure
 
Last edited:
Dextro .45 said:
Cocaine isn’t your typical DRI ….like Bupropion (Wellbutrin)

Cocaine is strikingly similar to Methylphenidate (Ritalin), both being classified as “Inverse Aginists” which release monoamines DAT/NET/SERT in addition to inhibiting their reuptake, resulting in Dopamine building up in the CNS

Cocaine is………………….DAT>SERT>>NET (dopamine & serotonin predominant over norepinephrine)
Methylphenidate is……….DAT>NET (3-4x more dopamine release over norepinephrine)

Methylphenidate (Ritalin) is actually nearly twice as potent as Cocaine at DAT (ED-50) effective dose to inhibit 50% of dopamine transporters DAT which is required to experience euphoric effects

That’s why they call Ritalin “Kiddy Coke” as it’s nearly identical in its MOA and given to kids with ADHD
First time trying Ritalin 20mg tablet I was euphoric & happy, robust mood-boosting properties with minimal cardiovascular negative effects such as increased HR & BP. Safer than the typical amphetamine medications, excluding Dexedrine & Desoxyn

So you wanna blast Cocaine and jerk off for maximum dopamine release lol.

Pitter padder…..

You want more pleasurable dopamine release? Take an oral Speedball lol. No, really :)

Oxycodone 10mg & Methylphenidate 20mg orally administered SUPER EUPHORIC
Cocaine & Heroin I.V. injection ……BOOM 100% Pure Ecstasy

Opioids are SUPER euphoric & pleasurable…adding a dopaminergic stimulant practically Triples the Euphoric Pleasure
Click to expand...
Thanks...was just wondering if additional dopamine would make a difference.

I'm never trying heroin in my life as that's something I don't wish to ever start.
 
ageingpartyfiend said:
That's exactly why some poor fuckers get addicted to stims plus porn

Massive dopamine overload - strong new neural pathways
Click to expand...
Honestly, I was more hypersexual with cocaine and methylphenidate than with amphetamine-type stimulants. I know one just blocks DAT and NET while the other is both a blocker and an NDRA (so in theory it should make me "hornier"). But for some reason this particular side effect (hypersexuality) is more pronounced with cocaine and methylphenidate, but with cocaine I get both horney and end up succumbing to coke dick.
 
I just read this a cringe, not at yall. At my own shamefulness. I used to wanna just do pure meth and have sex until I landed myself into a pickle where everything I went through I deserved and worse. I will never gain that trust again 4 my ex. I have to absolutely accept it. I can careless about sex anymore. It just doesn't have the draw it once had. You can flood your dopamine so much you end up psychotic and thus reaping what you in your own heart has sown. I would like to prevent this but ppl just wanna do what they wanna do. Screw the ramifications.
 
I've devoted my entire life to celibacy till the end of the line cuz I won't find any other who can replace her.
 
Lol yeah im with you man i just tend to find cocaine and loud music is the best followed by nitrazepam for the comedown haha
 
KirkhamBadMan said:
Lol yeah im with you man i just tend to find cocaine and loud music is the best followed by nitrazepam for the comedown haha
Click to expand...
I sometimes do it in the back of a van at noon , so coffee and sandwich time. 😄. Makes long journey go better. But can't dance about or race around like a hamster lol
 
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