Well I am not a doctor or chemist, but I can tell you from personal experience, that grapefruit juice is a good way to enhance some drugs, but not all and that is key. Like, it will definitely work for valium, even says so as a warning on my bottle label, and it seems to do the same thing with a few other drugs, like Soma, but I really cannot say that it helps potentiate any other drugs any better, and as far as Tagamet--yes, but only on certain drugs, not all. Like I was totally surprised by what happened one day when I had severe indigestion, and I took a tagamet, and about an hour later, had just received some Soma and took my usual 4 or 5 and man, was I sorry I had taken that many THAT day. I was falling over the place, stumbling, and eventually passed out for about 3 or 4 hours. AND that had never happened before with only 4 or 5 Somas. That many is usually just a TEASER for me, if I really [/COLOR]want to get wasted on Soma, it takes way more than that, but that day, it had to be the tagamet I had taken about an hour before.
Someone in here said something about smoking. As a smoker myself, for over 30 years, I cannot honestly say that it enhanced my reaction to pain meds, but it sure did increase my craving for a cigarette so badly that I could hardly wait to get outside so I could light one up. It is common knowledge amongst the medical field that smoking and using BENZOS, WILL definitely DECREASE the effects of certain benzos, but not enhance the effects at all. Maybe that works differently for pain meds but not for benzos.
I just use the old grapefruit and tagamet tricks for all controlled drugs I get, just to see what happens, nothing really all that dramatic has happened, except with the Soma that day I had taken tagamet.