Great post. Any tips on the saline to drug ratio OP? Right now I'm using a needle-less insulin syringe and fill it with 3-5 drops COLD distilled H20, squirt it into the bottom of my pill crusher, let the HM dissolve into a "slurry" squirt it up there, let it sit for about 15 mins or so, then blast 2 pumps saline to aid in absorption. I think i'm not using enough water, it's about 3-5 drops. I remember using a droppers full and getting a REALLY good effect but had to keep my head tilted back for around 15-20mins which can be annoying unless you're watching a flick/laying down. Anyone care to give any advice/tips? OP? I know hydromorphone is VERY soluble in water so I guess I'll have to find the "sweet spot" myself...This should be a mega-thread!!! Far as the clinical trials they're actually finishing phase 3 this month, so keep your eyes peeled for Dilaudid nasal spray sometime this year hopefully...My Dr. said he'd prescribe it soon as it hits the market [bad nerve pain in arms] Man I love that guy. For now i'll have to play Dr. Hydrostein haaa..[I'm prescribed name brand Dilaudid by Purdue Pharma 4mg IR] Be safe, Peace! %)