I have been taking hydrocodone over the years for a bad hip. Before it would make me itchy, energetic and almost always make me throw up. I would get the awesome euphoric feelings with it too. I just recently had surgery on my hip because i finally found a competent dr. He prescribed hydrocodone 10 mgs. They did not have the same affect on me at all! They made me extremely tired, would doze off where before i could pull all nighters on them, i never felt nauseous this time no matter how many i took. My nose itched but not an all over itch like it used to. The first pills i got said ip110 and then my refill from a different pharmacy said Watson853 but they didn't have the good affects either and my pain was not very controlled with either type. I was just curious if anyone else has heard of this happening or is it all just in my head? I was actually excited about the euphoria that i had experienced in the past but got nothing. Thank you.