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EpiPen and vasoconstriction

asecin

asecin

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Joined
Apr 13, 2005
Messages
1,725
hi, unusual question but i post it here because i need professionals opinion on this. EpiPen is epinephrine injected directly which causes vasoconstriction. it is prescribed for allergic reactions and it can be lifesaving, but i have this weird question. considering its vasoconstriction activity, what if injected into the penis, can it shrink?? dont ask why i ask this, i just have to know :s
 
If the background to this is that you've taken too much viagra or something - mixing vasodilatators and vasoconstrictors is quite dangerous. Don't do it, better seek medical help if you think something's wrong.
If this is some sort of fetish - don't do it.
In general: don't do it.
Also, apart from the application site (genitals are not suitable!) the effects are systemic (that's what the pen is for after all), so that's another consideration.

Epi pens are not for injection into the penis (sorta should go without saying).
 
what do you mean? what would happen? why there are no reports on this im not sure if its dangerous or not. i was reading about how it is used, and its for muscles in legs or arms, penis is also a muscle. it makes sense it might work.
ok, lets assume its not a good idea. what else can i use as vasoconstriction there? ive tried cocaine and amphetamines but those vasoconstrict my whole body and you might get a stroke. i need the vasoconstrictive effect of coke and amphs without affecting my whole body
 
What do you mean why are there no reports no this? I'd suppose not many people get the idea to ram an epi pen into their penis.
Btw, the penis is not a muscle (hence no site for intramuscular injection). And an epi pen also affects the whole body as I've written above, otherwise it'd be useless for an (not only local) anaphylactic reaction.
 
Yes, epinephrine injections in your pecker will make it shrivel, this is because epi is a "fight or flight" and most animals do not reproduce while being chased by predators.

I seem to recall adrenergic agents being used fir priapism (long lasting boner) ... but as others have said the needle on the EpiPen is a big IM needle that would shishkabob your weenie.

The problem with epinephrine is if any gets into the rest of the body the effects are quite unpleasant, and also it is relatively short acting. Maybe diluted 1:20,000 and applied like dental anesthetic with a very fine needle it could cause localized vasoconstriction but I personally find that even in that usage form it is still cardiotonic/mildly anxiogenic.
 
what do you mean "shishkabob your weenie"? would it really cause long term damage? and yes, im aware of some nasty effects from epinephrine but its so short acting, it wouldnt be a huge deal i assume. in comparison, cocaine and amphetamines shrink my dick but are long lasting whole body effects make me sick over time i rather not use them anymore at all. i was about to have a stroke last time. and what for, because of arousal? i assume epipen wont at least cause such problem as stroke or heart attack hopefully because it is short acting and is far localized in the penis than any other area of the body. i dont think it will have such a giant whole body effect from there but who knows unless theyve tried right.
sekio, can you remember which adrenergic agents are used for priapism? l guess ill google threatments for priapism on google and have something like that which is probably safer? perhaps, yes
 
I'm pretty sure alpha agonists such as phenylephrine injected i.d. (intra-dong) are used for priapsim.

Since the penis is not a muscle, a needle used for intramuscular injection (and an auto injector at that which is designed to punch through pants) is definately a bad idea.

Which is not to say that self administering phenylephrine in the manner a physician would is a good ideas but there are degrees of bad idea. It's like the difference between fighting a hippopotamus, and fighting a hippopotamus while slathered in burning pitch.
 
asecin said:
what do you mean "shishkabob your weenie"? would it really cause long term damage?
Click to expand...

As the others already said, an autoinjector like an EpiPen is not some dainty needle for IV use - it's a spring-loaded device for medical emergencies, intended to drive that needle over half an inch into your muscle, with enough force to punch through clothing if necessary. For obvious reasons, even in the event that something has to be injected into your dick, you would probably want to have it done by a careful, relaxed and well-trained professional, not a fucking steel spring.
 
half an inch needle? piercing through pants?? ok! im not scared of needles, but it seems scary to do that in the penis.
about phenylephrine, i brought a lot from a store year ago and took mega doses orally, and it didnt do anything. i suppose there is no other way but to be injected? that is such pain in the ass since i cannot do it by myself even though its easily available as pills.
anyway, i dont wanna discuss this topic any further hah its already weird. i guess ill concentrate on some of those alpha agonists and see urologist for better analyses
 
asecin said:
about phenylephrine, i brought a lot from a store year ago and took mega doses orally, and it didnt do anything. i suppose there is no other way but to be injected? that is such pain in the ass since i cannot do it by myself even though its easily available as pills.
Click to expand...

Yeah, the use of phenylephrine as a replacement for pseudoephedrine in oral cold remedies is somewhat controversial, since a number of recent studies have shown it to be no different from placebo, even at greatly increased doses.
Basically, it lacks pseudoephedrine's alpha-methyl group which would suggest it gets easily broken down by monoamine oxidase, and its extra hydroxyl group further decreases its bioavailability.
 
They sometimes give out injectable phenylephrine for recurrent priapism. (To the patient.) Epinephrine works but using an EpiPen would be way too much, too large. There are some hormonal agents as well, but probably not for some purposes. I've heard of baclofen for some neurological cases, but not sure how common or effective that is.

But don't go mixing or injecting it if you don't need it. I can't vouch for the veracity of this anecdote, but...supposedly there was a sickle cell guy at GW hospital who basically lost his dick and had some bad ischemic/occlusive event when overusing injections, supposedly to try to not have a reaction to gay material.
 
i keep having priapism though. its a nightmare and im scared to go to the ER since they know me there from all my recurrent heroin ODs. so, im in a lot of pain lately and my dick is turning into purple potato from all those long lasting errections. its a fucking nightmare. not sure how to go on from this. i just wont go to ER for this, EVER. is just finding a good urologist my best option?? please give me a good advice!
 
Yeah, find a urologist, preferably one who knows a good amount about priapism/resources. It can be worth a trip to an ED if it is getting worse, there could be vascular factors or other reasons at play. I can understand the reluctance given a history with an ED, but it can be a damaging condition and pretty painful. But in place of that, and if you are stable, a good urologist may cover it.

A few (many now) years back I had these episodes with general muscle weakness and persistent, long-lasting erections that were unnerving. Eventually for me they said it was some temporary weird reaction off of antidepressants or something, almost like a sympathetic/parasympathetic partial seizure (hair standing on end/ pupils/weakness) but yeah.

Keep going! If you get a bad episode do consider an ED, there could be flow/vascular/other reasons to review in an ultrasound, that could be dealt with acutely, with a shunt or whatever. People get these things and the EDs can deal with them.
 
ED? i dont have erectile dysfunction dude. its opposite. maybe you meant ER.
anyway, ill never go to ER with full on erection complaining of priapism ever! thats insane. last time on heroin OD i didnt even have underwear and they freaked out, imagine discussing my sex organs in general... thats fucked up. ill probably look for good urologist, yes.
 
Emergency Room (ER) vs. Emergency Department (ED). The systems I've been with usually do EDs.

I mean emergency departments deal with a lot of stuff, no need to let some sense of perceived propriety block treatment/ care, if necessary for expedient care. Bowels, genitals, infections, everything. Priapism visits for sickle cell crises, for example, aren't unheard of.
 
asecin said:
anyway, ill never go to ER with full on erection complaining of priapism ever! thats insane. last time on heroin OD i didnt even have underwear and they freaked out, imagine discussing my sex organs in general... thats fucked up. ill probably look for good urologist, yes.
Click to expand...

Sounds like a way better idea than injecting your dick with an epi-pen. Quit being an awkward teenager and go talk to a doctor about a legitimate medical problem. At least, if you value your penis anyway.
 
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