• BASIC DRUG
    DISCUSSION
    Welcome to Bluelight!
    Posting Rules Bluelight Rules
    Benzo Chart Opioids Chart
    Drug Terms Need Help??
    Drugs 101 Brain & Addiction
    Tired of your habit? Struggling to cope?
    Want to regain control or get sober?
    Visit our Recovery Support Forums
  • BDD Moderators: Keif’ Richards | negrogesic

DXM what is the best time of the day for a 300mg trip.

Mracid

Bluelighter
Joined
Jan 26, 2015
Messages
532
I decided that tomorrow I will be using DXM for various reasons. First I will describe my plan then ask for further insights on how to reduce possible side effects and possible onley's lesion (I think that counts as harm reduction? right?)
I read a little about onley's lesions and came up with some infos, so I plan on taking everything I know can help avoid them, and since I will take a fairly low dose and am really not a dissociative user, I have done it about 5 times in the last 4 years I have even lower chances of creating them but there is no impossible when we are talking about biochemistry. (also I am not worried about psychic effect, I am really experianced with psychedelics and went places which I didnt know existed without being ready and came back fully sane.

So my plan is to take a medium amount of DXM about between 2nd and 3rd plateau, I will also use to prevent onley's lesions:
-1/2 tab to 3/2 tab of LSD depending on the time of the day I start the trip
-Low amount of clonidine (also to lower BP)
-Lots of rooibos tea to prevent free radical damages to the best I can,
-Noopept for neuroprotection (also to help memory formation)
-L-theanine to reduce possible stress and protect neurons from oxidative stress
-B-complex and D vitamin to avoid depletion
-Medium amount of benzo (also to lower BP and possible but quite unlikely, to lower anxiety)
-And low amount of DPH in the middle or at the end of the trip (about 50mg, also to reduce muscle tension/ soreness)

I will also avoid caffeine, my ADD med, and pretty much anything that can increase BP and heart rate.
I will also take Magnesium supplements for muscle cramps, and plan on staying home watching movies/ any kind of TV and music and meditation/energy manipulation, so nothing disturbing, my parents will be home but I am 19 and they know all about my history with drugs (over 200 psychedelic trips but mostly serotonergic psychedelic, but never tried coke or MDMA or basically anything that has danger of either addiction or intense neuronal damange) and they usually don't notice that I am high no matter what drug I take, I once was on 7/2 tab of LSD and they didnt notice, so no stress there, in fact I like being with my parents while tripping it makes me feel closer to them. But I digress.

My only questions regarding this trip are;
1-during a DXM trip I know sedation can be a factor but do I want to be still tripping when I go to bed? or just finished tripping? or spending some time awake after tripping before bed. Reason I ask is because I am susceptible to insomnia and was wondering what time to dose to make sure I don't get insomnia after the trip. Becasue if the comedown is an upregulation of NMDA receptors it can lead to insomnia and overstimulation.

2- Does any1 know anything else than what I mentionned to reduce the chances of onley's lesion, I found that psychedelics, benzo, antioxydants, vitamins, alpha2 adrenergic agonists and some other chemicals can help but does any1 know about other kind of supplements/herbals that can help avoid it (other than those I mentionned).

Basically I want to have a trip that lead to the lower amount of possible insomnia and lower amount of possible onley's lesions.

(sorry if the text seems a little disorganised I did the best I could, and if this better fits in the phamacology section I'd be glad that it is switched there).
 
1. You need to figure out what your preferences are. We really can't provide them for you. You might prefer tripping in the evening, after coffee, while having sex, on a boat, in Zimbabwe, while reading economic theory and everywhere in between. You will need to decide what you like best.

2. Olney's Lesions are generally accepted to not be a huge risk with Dextromethorphan. Some sources claim that they are a real risk, but the concensus of the medical community seems to be that you only risk danger by using extreme dosages, constantly, through a route like injection. Taking one trip is most likely not going to be sufficient to change anything in your brain permanently.
 
Thanks for the reply I agree I might have taken the lesion too seriously but I prefer take it too seriously rather than not enought :p.

Also I don't think I have preferance other than not having killing insomina today. I planned to take it around 11am so that I have some time after the trip to get rid of the residual stimulant effect, do you think it is a good idea? or would it be better to start sleeping still in the trip? I plan on taking a high 2nd plateau which is in the middle between still stimulating starting to be sedating. thats why I kinda hesitate. All I care about is insomnia.
 
I would say that taking the drug by 11:00 am would practically eliminate the potential for total insomnia. You should be able to make it to bed around 9 or 10.
 
Great, glad I took it at about 10:40! Thanks for the report, so far its been an hour and a half and only feel slight effect, and took half a tab of LSD to make things more visual about 20 mins ago, I took about 300mg but am thinking of upping it to 350 to 400mg since I dont really feel it, but before taking a decision ima wait at least another hour.

BTW I weight 55kg.
 
In my experience, Dextromethorphan can take a while to kick in. I'm not sure if this is true for everyone, but it's usually like 1.5 hours for me, so be careful about redosing.
 
Did not redose, got everything I wanted from the trip and had no nausea, overal a good one!

I don't think I will have insomnia as I am fucking tired. Thanks for the insights.
 
If those leisons exsist then I must have them because i took 240 to 480 mg almost everyday like 6 days a week for like three years.
 
It was proven that they exist in rats and mices, but they were only speculated from symptoms in humans, a specialist posted an article on them in erowid, he isolated the region where they happened in animals and listed the symptoms that would appear if it happened to humans and it correlated to the symptoms alot of HEAVY users were reporting after long term use of high dosage.

I don't really know how high the dose has to be nor the frequency that is needed for them to happen but it looks like humans are not shielded from them it seems that we are just more resistant to it than animals, meaning we can take more, more frequently without creating them but it doesnt mean they don't happen. Also he said that some are more enclined to getting them while others are less.

So basically there is no real way to know for sure if some1 has them, it would be mere extrapolation originating from perceptual changes.
 
Did not redose, got everything I wanted from the trip and had no nausea, overal a good one!

I don't think I will have insomnia as I am fucking tired. Thanks for the insights.

I'm glad you enjoyed it. For me, Dextromethorphan is an automatic ticket to Dysphoria and Anxiety. I had a really bad experience once where I took some in the evening and ended up falling asleep and had a very real-feeling dream where I was in a plane crash and died, however you choose to interpret dreams, it was really intense and the intensity of thinking I was gonna die caused me anxiety for the whole next day. I don't mean to sound dramatic.
 
According to his paper these lesions occured in rats at 4.29 mg per kg for pcp and 40 mg per kg for ketamine subcutaniously

Thats 50 to 100 times higher than recreational doses! Literally otc pain relieviers and alcohol produce not just some change in some part of the brain that can be detected but complete death at a lower ratio of active dose to death
 
Agreed, thats why I do not drink nor take any OTC painkillers. I am kind of really protective of my neurons, mabe a little too much but like I said, better be too careful than sorry with those things.
 
Top