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Drugs inbibition cytochrome p 450

3dmusic

Bluelighter
Joined
Sep 9, 2005
Messages
930
Im not a neuroscience or pharm expert, im a layperson but I figured someone with more knowledge in this field could help me.
I used approx 200mg of codeine on Friday and for the last week, have been using amitryptiline. Amitryptiline inhibits codeine.
I have also been using cbd oil, and that inhibits both, does that mean that I will have to wait weeks if I want to use antoher opiate without getting habituated.
I have had one habit in the past so i know its easier to get rehabituated but I want days where I have a break from the unbearable anxiety and depression that has shrunk and restricted my life for months now, its unbearable. im tapering pregabalin and valium simulatanesously as I cannot afford to taper one at a time, not enough money to buy.
thanks in advance
 
I assume what you mean is specifically how the enzyme p450 cyp 2d6 converts codeine to morphine. I only used Wikipedia but it said the antidepressant is a substrate so atless it is strong inhibitor I wouldn't worry
 
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