Ether, mixed with approximately 2 volumes of alcohol to form ether spirit
was formerly used as an orally administered preparation for treatment of gastric flatulence and milder forms of gastralgia.
(also, curiously)
Intravenous administration of up to 1000 mL of a 2.5 to 7.5% solution of ether (
sekio note: ether is slightly soluble in water) in isotonic sodium chloride solution and 5% dextrose solution has been
formerly employed to quiet manic patients.
Osol, A., and R. Pratt. (eds.). The United States Dispensatory. 27th ed. Philadelphia: J.B. Lippincott, 1973., p. 507
[ref]
They sure used to have a lot more fun in the old days. Stomachache? Have an ether-and-alcohol cocktail. Manic episode? Ether
directly into your veins. (Probably nicer than Haldol/Risperdal)
I do not know what the effective oral dosage of ether is: the few times I have used it recreationally were always via inhalation because it allows for safe titration of dosage. Too much ether in you is unsafe before you reach the LD50 simply from the risk of falls, vomiting, positional asphyxia etc.
Pure ether boils at 35°C so ingesting it neat is not a smart idea. Due to this, it mainly leaves the body via evaporation from the skin and breath. So no matter how you get it in you, you will smell like the
Exxon Valdez for a good day or so, and be tasting it intermittently for up to 3 days. Plan accordingly. (Would be a good time to start trying new colognes, smoking/vaping a lot, and chewing gum obsessively.)