OpioidDopioid
Greenlighter
- Joined
- Jul 9, 2015
- Messages
- 23
I have Crohn's Disease (IBD), and several years ago had my entire Colon and portions of the large and small intestines removed.
Prior to these major surgeries I had been prescribed Opiate pain medications periodically, and they gave a fantastic high. 10-15mg at that time would have me floating, and a really nice warm sensation down my spine. The warm sensation is my favorite part of Opiate use.
Since I had the surgery, though, these medications seem less effective. I can take 15-20mg of Hydro or Oxy Codone with little effect. I'm wondering if my lack of a Colon would affect the absorption of these medications? I'm not extremely knowledgeable on the biological processes of opiate use, but I believe the Liver metabolizes most Opiates into Morphine which is what causes the effects. Would not having a Colon cause less of the drug to find it's way to the Liver, though?
I've also taken Kratom daily for several months now. I know there is some cross-tolerance there. However, taking 8-10g of Premium Kratom Powder seems to yield better results than 10-20mg Oxy Codone. This doesn't seem right as I know Kratom is considered very weak in comparison to legitimate Opiates.
Any insight would be appreciated.
Thanks.
Prior to these major surgeries I had been prescribed Opiate pain medications periodically, and they gave a fantastic high. 10-15mg at that time would have me floating, and a really nice warm sensation down my spine. The warm sensation is my favorite part of Opiate use.
Since I had the surgery, though, these medications seem less effective. I can take 15-20mg of Hydro or Oxy Codone with little effect. I'm wondering if my lack of a Colon would affect the absorption of these medications? I'm not extremely knowledgeable on the biological processes of opiate use, but I believe the Liver metabolizes most Opiates into Morphine which is what causes the effects. Would not having a Colon cause less of the drug to find it's way to the Liver, though?
I've also taken Kratom daily for several months now. I know there is some cross-tolerance there. However, taking 8-10g of Premium Kratom Powder seems to yield better results than 10-20mg Oxy Codone. This doesn't seem right as I know Kratom is considered very weak in comparison to legitimate Opiates.
Any insight would be appreciated.
Thanks.