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Misc Does blue lotus(Nymphaea Caerulea) contain maoi?

TDO90

Bluelighter
Joined
Jan 7, 2018
Messages
46
Hello, I was wondering if there's any chance that Blue Lotus contain any maoi's? I did some online search after already drinking the tea and some people say that blue lotus is maoi but I can't find accurate information. It would be very problematic for me since I also take 40mg Prozac and 40mg Vyvanse :(
Here's the full compound of blue lotus: Lotusine, demethyl coclaurine, neferin, and nuciferine
Anybody on here have any experience with blue lotus? Thanks :)
 
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It appears that B Lotus is not an MAOi and poses no real interactions with fluoxetine as the AD effects are likely due to it's Dopamine agonism, yet still strange as Nuciferine is an antagonist / inverse agonist. Not going to dive into that mother nature mystery but as far as pubmed and a consensus of anecdotal reports, an AD interaction that could be seen as dangerous is absent. The effect it has on lowering blood sugar seems to be the major concern where an interaction is listed (for diabetes meds).

I think it would still be best to proceed slowly as the Vyvanse could possibly interact as well as it also has a role regarding dopamine. Though nothing was listed for it either across several places, it could still possibly make you feel crummy. Maybe some BL'ers with specific AD + Amp + B. Lotus experience might chime in.

"The blue lotus flower (Nymphea caerulea) is an Egyptian water lily containing apomorphine and nuciferine. Apomorphine has been described as a psychoactive alkaloid and is a non-selective dopamine agonist primarily used to treat Parkinson's disease as it stimulates dopamine receptors and improves motor function. Nuciferine is an alkaloid associated with dopamine receptor blockade."

https://www.ncbi.nlm.nih.gov/pubmed/28266899

https://www.ncbi.nlm.nih.gov/pubmed/26963248
 
It appears that B Lotus is not an MAOi and poses no real interactions with fluoxetine as the AD effects are likely due to it's Dopamine agonism, yet still strange as Nuciferine is an antagonist / inverse agonist. Not going to dive into that mother nature mystery but as far as pubmed and a consensus of anecdotal reports, an AD interaction that could be seen as dangerous is absent. The effect it has on lowering blood sugar seems to be the major concern where an interaction is listed (for diabetes meds).

I think it would still be best to proceed slowly as the Vyvanse could possibly interact as well as it also has a role regarding dopamine. Though nothing was listed for it either across several places, it could still possibly make you feel crummy. Maybe some BL'ers with specific AD + Amp + B. Lotus experience might chime in.

"The blue lotus flower (Nymphea caerulea) is an Egyptian water lily containing apomorphine and nuciferine. Apomorphine has been described as a psychoactive alkaloid and is a non-selective dopamine agonist primarily used to treat Parkinson's disease as it stimulates dopamine receptors and improves motor function. Nuciferine is an alkaloid associated with dopamine receptor blockade."

https://www.ncbi.nlm.nih.gov/pubmed/28266899

https://www.ncbi.nlm.nih.gov/pubmed/26963248

Thanks so much for the information that you provided. I absolutely felt nothing from 10 grams of blue lotus but fortunately no side-effects.
 
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