This thread title is funny. I've been through different friend "groups" here and there, but my "main" friends from hs don't even do hardcore substances. But they do drink (alcohol) a lot, and smoke weed here and there.
The friends I met after I moved away from my hometown were the ones who did too many drugs of all kinds; basically any and all they could get, and they have a lot of connects. (It's actually them that I'm getting the hcl mescaline from.)
But most likely no one could tell they use to trip too much, or even at the time that they did, though they still do til this day. Well, nowadays, it's set on the weekends. They'll do any psychedelic, they IV/IM and insufflate everything, etc. They work hard but also party hard too. Well, there's probably one or two of them that I would consider...bums. Those few always trip, and "hear colors and see music" too much, lol.
And in between these two groups, I met my ecstasy friends who I don't keep in touch with anymore. Well, most of them actually. Five of them I still chill with once in a while, and one of them being my gf who I live with. There were around 20 of us but damn, so much drama happened so we all split. The five of us made a faction while the others just dispersed on their own, as far as we know. Long story, but yeah, they definitely dropped too much and also smoked weed every day. Some were...umm...weird as hell. One of them lost it all to hell off of a 2g shroom trip. It's funny because another didn't brush his teeth (you could tell when he smiled because of all the gunk on it) or take care of himself that well, and he was a meth head. The rest were pretty normal but also too emotional, which caused the drama (plus immaturity left and right).
Anyways, I've said too much. But yeah, the whole brushing his teeth thing made me respond because I knew of someone that was just like that.