Fluid balance is part of the constipation equation, in fact, centrally-acting anti-diarrhoeals do their work by slowing down peristalsis so that the intestines have a chance to draw out more water from the stool, and probably why getting Miss Emma, DHM, or Dilaudid, or Vilan or Paralaudin in hospital is often mixed into a saline and goes in via a drip or syringe driver . . . there are also mild laxatives which can be administered mixed into a saline or glucose drip . . .
The "Coke Shits" on the other hand definitely comes from cuts like manmnitol, sorbitol, sometimes caffeine mixed into the C-Jam to bulk it up; a lactose-intolerant person can have explosive flatulence and/or diarrhoea if the Bolivian Marching Powder was cut with both milk sugar and mannitol. Some dealers apparently do put stimulant laxatives into smack in particular -- maybe they see it as a public service because of the constipating effects of smack . . . Some but not all dionine, codeine, dihydrocodeine, dihydroisocodeine, nicocofdeine, hydromorphone, benzylmorphine, nicodicodeine, hydrocodone and IIRC some normethadone, levomethadone, isomethadone, propoxyphene/levopropoxyphene, noracymethadol and methadone cough medicines contain sorbitol and/or mannitol, perhaps for that reason or as an alleged deterrent to customers slamming the whole bottle at once and pouring 120-500 ml of cough syrup into one's gullet in one go . . . I see in an old formulary that smack cough syrup did not contain sorbitol or mannitol, but terpin hydrate was a popular ingredient used essentially the way guaifenisin is now . . . I know that heterocodeine was considered and/or used as a strongly analgesic and sedative cough medicine but Ithat is all I have seen; . . . By the way, the cough suppressant pholcodeine is also known as homocodene, and pseudocodeine, a minor opium component, is known as bicodeine.
