DOSAGE: greater than 1000 mg.
DURATION: unknown.
QUALITATIVE COMMENTS: (with 500 mg) Nothing.
(with 1000 mg) Nothing.
(with 10 mg i.v.) RNothing.
(with 1000 mg of 3,4-dimethoxyphenylacetic acid, a major human metabolite of DMPEA) RNothing.
(with 500 mg of N-acetyl-3,4-dimethoxyphenethylamine, a major human metabolite of DMPEA) RNothing.
EXTENSIONS AND COMMENTARY: Why all the interest? Why keep pursuing a compound that is so obviously without activity? Or a metabolite that is also without activity? The answer is that these are totally fascinating compounds just because they have no activity! By the way, in this instance, I actually made up most of the quotations. I am not sure that the subjects actually said, "Nothing," but they did report that there were no effects. In my own experiments, my notes record the phrase, "No effects whatsoever."