It's hard to predict anything about this because SAR's are generally predicted through experiments. For example, with amphetamine the potency increases with the addition of one methyl group (methamphetamine) but drops drastically with two methyl groups (dimethylamphetamine). However, with methylenedioxyamphetamine (MDA), the potency decreases with the addition of one methyl group (MDMA). Furthermore, for cathinone, the potency increases with the addition of a methyl group (methcathinone). Since methylone/bk-MDMA lies between these two groups, it's hard to really say.
What I can say with relatively good confidence is that if ingested orally, it is likely that the dimethylone will be demethylated during metabolism to it's respective metabolite methylone (. Since the enzymes typically do these processes at less than 100% efficiency, dimethylone will probably have some characteristics similar to methylone because there will actually be methylone in one's system after ingestion. However, this doesn't mean that one should take more to achieve an equipotent high to methylone since dimethylone is also a drug in itself and the potency of it is not known.
Personally, I'm predicting that it will be weaker than methylone but still can be used in a similar manner to methylone. If one does not have access to methylone, then this might be a good substitute for it.
