Difference in Cannabis High After DXM Trip

[aujiraman]

I normally get pretty high tachycardia from smoking cannabis (sometimes 170-180+ bpm), especially when I an on DXM (which is rarely). One thing I have noticed, however, is that my tachycardia rate from smoking is not *nearly* as high on the day/s after a DXM trip. Still I'm blazed, but the heart rate stays around 110-120.

Could this be due to an increase or reduction in serotonin or norepinephrine levels the day following a trip? What specific effects does a moderate DXM trip (2nd plateau + cannabis) have on neurochemistry / brain structure that lasts through a sleep cycle into the next day or into the following days? Do we even know these things?

 

[PotatoMan]

High amounts of serotonin.

This causes good and bad effects. Hot flashes, muscle tremors, bruxism.

The good effects are 0 anxiety, total contentness.

I think U experience this calmer weed high because of the high serotonin.

I know what ur experiencing. it's pretty trippy to smoke weed, drink, cigs or coffee after a dxm trip.

 

[ecstacylover]

I've heard before that NMDA antagonists decrease tolerance or block tolerance to a variety of substances, including cannabanoids. I do know that the days after using dxm or mxe that I smoked weed I get unbelievably high off even small amounts often to the point that is uncomfortable.

 

[aujiraman]

This causes good and bad effects. Hot flashes, muscle tremors, bruxism.

The good effects are 0 anxiety, total contentness.

I am getting mostly the good ones. No hot flashes, have noticed a twitch here and there (mostly in my legs). I already suffer from mild bruxism from anxiety - if anything, mine has gotten better. Very balanced today - I feel "cleansed" in a way. If only this feeling would last...

I think U experience this calmer weed high because of the high serotonin.

I started to think the same thing, but then I remembered the time I took a dose of 5-htp (a precursor to serotonin) and then smoked. I had a severe panic attack. Felt nothing at all like today.

I know what ur experiencing. it's pretty trippy to smoke weed, drink, cigs or coffee after a dxm trip.

I drank a pretty good swig from a fifth after coming mostly down (had never done this with DXM before). It gave me a rush like the first time I took Morphine - good feeling in the shoulders - like stepping into a hot bath.

 

[aujiraman]

I've heard before that NMDA antagonists decrease tolerance or block tolerance to a variety of substances, including cannabanoids. I do know that the days after using dxm or mxe that I smoked weed I get unbelievably high off even small amounts often to the point that is uncomfortable.

I get the same effect sometimes (from DXM, never done MXE) - however, if I smoke throughout the trip, I get this effect instead the next day - a more relaxed high instead of a more intense one.