If liver enzymes are elevated this can be tested for.
It also normally makes a person feel pretty sick, not just shitting a lot.
If you feel nauseous, green around the gills, and ANY tenderness around the stomach you should indeed have your liver enzymes checked.
Only one case study did I find where doctors argued that MDMA caused slow liver toxicity.
The young male patient had no adverse events while rolling, but over a period of six months or so he experienced liver failure.
Liver failure is normally such a severe event that people RUSH to the hospital and feel like they are dying.
Their hands and feet can swell like balloons, their face swells up and turns yellow...their body basically poisons itself.
It is horrible beyond belief and anyone that goes through it experiences nausea, diarrhea, and body sickness that is hard to imagine.
Most doctors believe that MDMA related liver toxicity is NOT caused by the MDMA.
It is part of the bodies immune response.
Serotonin is a critical component of the immune system, including temperature regulation.
Fevers on MDMA certainly endanger the liver...
My experience suggests that SWELLING at the top of the GI is a great cause of damage.
I had so much swelling just below my stomach that I feared bumping into to something.
I was CERTAIN that enough pressure would actually cause a rupture!
I cannot express how bad it was - I have NEVER felt so much pressure around my stomach before in my entire life!
The body destroys the liver in its attempt to control brain serotonin activity.
I do not believe that post-roll diarrhea is a result of altered liver function.
Severely hit the nail on the head - good job by the way.
The primary purpose of serotonin is to contract the smooth muscle around the intestines.
90% of your serotonin and serotonin receptors exist in the gut, not the brain.
Serotonin is considered the brain-gut circuitry, and it has a surprising (even miraculous) ability to evoke powerful emotions in people.
And damage to the serotonin system has an equally (or greater) ability to invoke suffering and loss of humanity!
Many people feel nauseous or have to SHIT when rolling.
I even took to using an enema at one point.
But I never had diarrhea, even the next day.
Perhaps loose stools but not true diarrhea.
Such an event calls attention to you DIET.
What are you eating around the time of the roll and the days leading up to it?
Poor diet is the greatest suspect.
Parasites are also considered.
I should point out that ever since my Serotonin Syndrome I have had MAJOR changes in digestion.
I didn't eat solid food for about a month afterwards, because every-time I did I felt EXTREME anxiety.
I could literally feel the food SCRAPING against my intestines all the down, and it tortured my brain. Physically.
It was like something was tickling my brain from inside my gut for HOURS. I'm shuddering just thinking about it.
I survived on protein shakes with lots of fruit in them.
Four weeks of weight loss and finding Piracetam is what allowed me to start eating real food again.
But I still had to be very cautious about my diet, as anxiety and head-pressure was directly linked to digestion.
At 6 months I was finally able to eat fast food again.
Even now at 14 months I still get mild head-pressure and what some people would call depersonalization as food passes through the lowest portion of my intestines.
It appears to me that my intestines have been rewired into my brain from top to bottom, with the colon being the last target during recovery.
For almost 8 months my bowel movements were either soft or unformed, like they just kinda fell out of me.
They still show signs of reduced colon contraction with only a few inches being formed and the rest formless.
Oh well, at least I'm eating whatever I want to and having regular daily BMs now.
Charming.
On the more socially acceptable side I am finally back up to normal weight.
I have been exercising like mad all year, so I'm sure that slowed it down.
I actually have more muscle mass than I ever did before. :D
Oh yeah - I almost forgot to mention that for the first six months I could NOT feel the sensation of nausea.
I'm dead serious - no matter how much vitamin C I took there wasn't a HINT of it.
I always used to get a little sick to my stomach on Vit C.
Nausea, I believe, is a symphony of brain activity - not a simple biological sensation.
When I finally started feeling nausea again I considered it a very good sign.
Don't worry too much about your diarrhea, just watch your doses and space them well.
A collapse of the intestines produces more problems than you can begin to imagine.
At least yours still work.