13 years later, variety of antidepressant medications, mainly cymbalta (10 years) and thousands of pounds on therapists, counsellors, alternative medicines and therapy, rigorous physical tests my doctors to determine any physical illness......still struggling with any motivation to get out of bed in the morning, only go to work because I've bills to pay but can't concentrate, living on caffeine to get myself through the day and a fairly unhealthy diet. I know I should want to help myself but I've gotten to the stage where I just want to give up.....I'm tired fighting this......I honestly don't know what to do and where to turn. I've came across niacin therapy...has anyone tried this? If so, what was your experience? I'm self employed and have to be very motivated to do my work, in the last few weeks, I've really struggled to concentrate and am on the verge of losing my clients. I could sleep all day everyday and literally don't see a way out