Burn it up
Bluelighter
- Joined
- Jan 25, 2009
- Messages
- 119
I was browsing through the Big and Dandy 3-MeO-PCP thread and found some cases of users that were taking low doses of the drug up to three times daily for extended periods of time (sometimes even years). So basically we are talking here of a chronic regime in which the user is almost all of the time under the effects of this arylcyclohexylamine.
As NMDA antagonists interfere with Long-Term Potentiation, I would expect these users to report some sort of cognitive impairment or learning and memory difficulties. However, users did not report any of these kind of problems throughout that use, neither did they need to substantially increase their dosage with time to reach the desired effects.
My question is, what could theoretically happen to a brain in which the LTP is chronically hindered? Should it not produce very discernible visible symptoms? Is maybe 3-MeO-PCP not blocking the LTP for some reason?
Thanks.
As NMDA antagonists interfere with Long-Term Potentiation, I would expect these users to report some sort of cognitive impairment or learning and memory difficulties. However, users did not report any of these kind of problems throughout that use, neither did they need to substantially increase their dosage with time to reach the desired effects.
My question is, what could theoretically happen to a brain in which the LTP is chronically hindered? Should it not produce very discernible visible symptoms? Is maybe 3-MeO-PCP not blocking the LTP for some reason?
Thanks.