Cyp2d6

[clubcard]

fixed - cheers!

 

[clubcard]

It looks like an electron-donating amide group is the key moiety. Beyond that, looks like a lipophilic pocket for the aromatic. Loratadine is interesting... but low MW chloroformate esters are in my 'things I will never work with' list.

I suppose the only other one people are likely to risk is mirtazapine. Neuroleptics, heart disease and cancer drugs aren't toys... so I think it's better dead than read, as opposed to the alternative.

 

[Keif' Richards]

So.. closing this one up!