I can't find much literature on the matter.
I remember I obtained some Clonidine like a decade ago when coming off of subs, but I don't remember it fazing me much or doing much.
Fast forward to now and I have first line resistant hypertension. With the first couple meds not working, doc finally prescribed me a Clonidine patch.
She doesn't know I still take .5-1mg of suboxone a day, sometimes oral, sometimes intranasal.
I put the .1mg/24hr patch on Wednesday, and she said continue to take my regular blood pressure meds on top of it. I felt okay that night, took my morning blood pressure med with it for the first time, felt a little heavy during my workout the next morning, like struggling to finish, and by that evening I was practically falling over drowsy and drunk. My blood pressure SHOT DOWN from 170/90 to like 103/53 in a matter of 24 hours. I was like HOLY SHIT this shit is strong, or maybe the pills I got a decade ago were bunk, but yeah I had to rip the patch off. My arms felt like they had 100lb weights attached to them, I was straight confused when making my food and fucked it all up, it was nuts.
So my blood pressure starts creeping back up the next couple days, I start feeling better, and I decide to let everything leave my system. I cut literally 1/4th of this patch and reapply it, and sure enough even that small of an amount lowered my blood pressure back into acceptable range, and I had super mild symptoms that went away compared to the whole patch.
Here's the kicker, the morning after (I applied the 1/4 of a patch the previous night) I did me my small line of suboxone I sometimes do (sometimes oral) to stave off withdrawals, and went about my workout and I noticed something really nice. I felt FUCKING AWESOME about an hour after sub ingestion. I'm usually beat after about 3 miles on the treadmill, or at least ready to get off and start weight training, but today I felt like I could have run another 10 fucking miles. Quite the opposite of when I first put on the whole patch and felt like I could hardly lift my legs.
Now I just put on another 1/4th of a patch because my body seems to be handling it better, and because I'm trying to keep it in my goal range of ~130/70, but its got me really curious about its interaction with buprenorphine. I know its use to help with restless legs and the like, but it seems to be in a different category of potentiator than the usual bunch. The only thing I read about it was out of 14 people who knew about it, 10 of them used it to "Use less heroin to achieve the same high".
So I'm used to just being on the bare minimum of sub to keep from total withdrawal, but this felt almost like an original opiate high, or like I'd taken a 2-4mg of subs as opposed to the .5-1mg I actually took.
I dunno just something to think about. I'll continue playing with the patch/sub dosage to find a good medium, but yeah I'm pretty excited.
Stay Safe - eBagger
I remember I obtained some Clonidine like a decade ago when coming off of subs, but I don't remember it fazing me much or doing much.
Fast forward to now and I have first line resistant hypertension. With the first couple meds not working, doc finally prescribed me a Clonidine patch.
She doesn't know I still take .5-1mg of suboxone a day, sometimes oral, sometimes intranasal.
I put the .1mg/24hr patch on Wednesday, and she said continue to take my regular blood pressure meds on top of it. I felt okay that night, took my morning blood pressure med with it for the first time, felt a little heavy during my workout the next morning, like struggling to finish, and by that evening I was practically falling over drowsy and drunk. My blood pressure SHOT DOWN from 170/90 to like 103/53 in a matter of 24 hours. I was like HOLY SHIT this shit is strong, or maybe the pills I got a decade ago were bunk, but yeah I had to rip the patch off. My arms felt like they had 100lb weights attached to them, I was straight confused when making my food and fucked it all up, it was nuts.
So my blood pressure starts creeping back up the next couple days, I start feeling better, and I decide to let everything leave my system. I cut literally 1/4th of this patch and reapply it, and sure enough even that small of an amount lowered my blood pressure back into acceptable range, and I had super mild symptoms that went away compared to the whole patch.
Here's the kicker, the morning after (I applied the 1/4 of a patch the previous night) I did me my small line of suboxone I sometimes do (sometimes oral) to stave off withdrawals, and went about my workout and I noticed something really nice. I felt FUCKING AWESOME about an hour after sub ingestion. I'm usually beat after about 3 miles on the treadmill, or at least ready to get off and start weight training, but today I felt like I could have run another 10 fucking miles. Quite the opposite of when I first put on the whole patch and felt like I could hardly lift my legs.
Now I just put on another 1/4th of a patch because my body seems to be handling it better, and because I'm trying to keep it in my goal range of ~130/70, but its got me really curious about its interaction with buprenorphine. I know its use to help with restless legs and the like, but it seems to be in a different category of potentiator than the usual bunch. The only thing I read about it was out of 14 people who knew about it, 10 of them used it to "Use less heroin to achieve the same high".
So I'm used to just being on the bare minimum of sub to keep from total withdrawal, but this felt almost like an original opiate high, or like I'd taken a 2-4mg of subs as opposed to the .5-1mg I actually took.
I dunno just something to think about. I'll continue playing with the patch/sub dosage to find a good medium, but yeah I'm pretty excited.
Stay Safe - eBagger