This is off topic & i found info on my OP through trial & error, but i'll answer your questions ongos:
No, not all ant epileptic drugs are abusable. none of the other ones you mentioned anyway. Gabapentin just happens to be an antiepileptic, as thats what it was originally approved for by the FDA.
but it is used for many other things these days since it is so weak (such high doses are needed) as an antiepileptic: now it’s used mostly as a treatment for neuropathic pain & anxiety, but also as a mood stabilizer. I’ve had life long issues w/ depression & anxiety & mood—and GBP is the only drug that has been effective in treating these, no SSRIs, SNRIs, SNDRIs, atypicals, tricyclics, tetracyclics, etc; they were all crap. But GBP allows me to finally function- I engage in my old hobbies once again, I’m able to converse & be comfortable around friends & family unlike before when I’d isolate in my basement 24/7 due to anxiety. So it certainly works for psychiatric disorders. But I’m no doctor & can’t tell you if it would help your OCD; usually SSRIs are the first line of treatment for this.
GBP was originally developed by Pfizer to mimic the GABA receptor & by theory create some action there w/ less abuse potential than traditional GABAergics. However, after human trials it was found to not even touch the GABA receptors, but, rather it affects several different areas: it interacts with voltage-gated calcium channels (most likely contributing to its antiepileptic action) & (from wiki) “it binds to the α2δ subunit (1 and 2) and has been found to reduce calcium currents after chronic but not acute application via an effect on trafficking.”
Some newer studies have shown that GBP facilitates GABA biosynthesis via modulating the enzymes glutamate decarboxylase and branched chain aminotransferase.Its been shown that GBP doesn’t interact w/ the traditional antiepileptic target areas such as NMDA receptors, glutamate, sodium or L-type calcium ion channels (like drugs phenytoin).
But yes, GBP can & is very recreational. Some people prefer its effects over benzos actually. It causes an anxiolytic effect w/ more stimulation, disinhibition , but sometimes w/ more unwanted (in my opinion) drunken like feelings/ataxia at higher doses (which tend to visibly affect gait & speech). However, these recreational effects diminish very quickly if used daily. You must take a few days breaks in between attempts to reach recreational effects to get that same feeling, the longer the break the better (however, my findings from my OP which I’ll post below my challenge that). However, for best therapeutic effect w/ neuropathy, daily use is recommended.. as it takes time to "build up" this positive effect.
have some obsessive compulsive disorder that I have dealt with for years and from what I have been told and from research it is the gaba-ergic drugs that have the power to destroy all OCD symptoms. True? GHB belong in this class of drugs as well, so is gabapentin a good candidate for OCD, if anyone knows?
Actually, SSRIs are used as first line treatments for OCD.. not GABAergics. & certainly not the recreational drug GHB, which is a GABA-b agonist & has a very different mode of action than most GABAergics on the pharmaceutical market today- which modulate the GABA-a receptor via targeting certain subunits to facilitate different GABAergic effects (z-drugs like ambien target alpha-1 GABA-a subunit for example b/c its more inclined to induce sleep).
Oh, speaking of anti epileptic drugs that's also reported in destroying all obsessions, Phenytoin is another one. So my curiosity now is, what's the deal with anti epileptic drugs and its many off label uses?
I think so many antiepileptics tend to have so many different off label uses b/c they tend to affect a wide range of receptor systems, depending on the drug. & i personally haven't heard of phenytoin "destroying all obsessions" as an off label use, but i could be wrong. AFAIK its primarily still only used as an antiepileptic.
