Changing the effects of dxm with bupe?

[Mr Crowley]

Do you guys think taking a low dose of bupe would block opiate receptors enough to reduce the sedative effects of dxm and it's metabolites?

 

[Pilll_head]

No, it wouldn't have any affect. DXM doesn't use the opioid receptors, I think the tripping is from NMDA receptor and serotonin receptor activity. DXM looks like an opioid but they aren't quite the same.

 

[zirbeldude2]

DXM potentiates opioids. But afaik not all of them.
It also seems to prevent developing opioid tolerance.