Not really, cocaine doesn't tickle the right receptors and you can't really turn it into something it's not.
Cocaine is just the way it is, it is too chemically distant from anything we can conceive of binding with a serotonergic receptor AFAIK.
Also I wouldn't try to modify cocaine too much even if you could model it for psychedelic binding properties, it is not a great starting compound - apart from the desirable psychoactive effects it is not good for the heart and analogues might be dangerously cardiotoxic.
Amphetamine happens to be a phenethylamine and there is overlap with psychedelics, like a continuum going from dopamine releasers to dopamine / serotonin agonists to serotonin releasers (not to mention NE).
Cocaine binds to transporters which is a totally different ballgame.... it causes reuptake inhibition like methylphenidate does but a little different, I don't think you could realistically make a psychedelic phenidate either.