It doesn't work that way. I think you're referring to precipitated withdrawal and thats if u take the sub too soon after doing heroin . The opposite, taking the sub then heroin, will just reduce or eliminate the effects of the heroin . Depending how much suboxone is left in your system. The more suboxone left inur system, the less high youll get. There is no magic, exact amount of time. Its different for each person depending on many variables.