123bupe123
Greenlighter
- Joined
- Mar 1, 2017
- Messages
- 34
Ive been on subs for about 8 months, suboxone for about 4 and subutex or just regular bupe for 4. Im on 16mgs/day. I went with just using it sublingually to intranasally to IV. Ive been researching the differences in the half lifes based on the ROA. There are conflicting reports on the IV half life as one lists it as around 2 hrs while another sites it at around 24 hrs. In my experience it definitely wears off fast. It feels like a decent shot lasts around 6-8 hrs before its noticably worn off. Im wondering about what you guys think and feel like intranasal use lasts and the half life on it compared to the 37hr halflife sublingually. I read a study that puts the Tmax (time to peak or time to max concentration) as 35 minutes and the half life at about 29 hours for intranasal bupe. Do you guys feel like thats the case? Sublingual's Tmax ranges from 45 mins to 2.5 hours
with the average (mean) half life of 37 hrs. Then bioavailability IV is 100%, intranasal around 44%, and sublingual
around 30ish%. Based on all this and experience, can anyone give me some of your opinions and experiences with the different ROA's and their half lives or to be more subjective, how long they actually last for you. Thanks.
with the average (mean) half life of 37 hrs. Then bioavailability IV is 100%, intranasal around 44%, and sublingual
around 30ish%. Based on all this and experience, can anyone give me some of your opinions and experiences with the different ROA's and their half lives or to be more subjective, how long they actually last for you. Thanks.