So this is only going to relate to a niche group but I wanted to get this information documented and out there. I am currently on a fairly low dose of Suboxone daily (2mg). I need to also state that I do not take 2mg daily but more like 3-4mg until im out. Im prescribed it every two weeks meaning I run out early. Every so often I will take a few large recreational doses of Immodium (lopermide and roughly 98-144mg per dosing) until I refill my subs. I wouldn't recommend this due to lopermide being cardiotoxic at these doses. The main point im getting at is that I had precipitated withdrawals from taking the sub to close to the lopermide dose. Yesterday I took 98mg of lopermide around 3pm. Then today around 4pm I did 3mg of suboxone IV and 1mg sublingually. Within 1 minute of doing the shot it became apparent I was going into precipitated withdrawals. However it only lasted about 45 minutes before symptoms were getting largely better. Now obviously lower doses of lopermide would not cause this but from my new experience there is a line with it that once crossed will trigger PWs. If anyone has any thoughts or questions, I would love to hear it. Be safe.
https://www.fda.gov/Drugs/DrugSafety/ucm504617.htm
-Immodium cardiotoxity warning.
https://www.fda.gov/Drugs/DrugSafety/ucm504617.htm
-Immodium cardiotoxity warning.