Yeah, its a sleepy kind of drug, it will sedate rather than stimulate, it also takes a bit of getting used to. I'm a prettyy sleepy mesured, aloof and icuy kind of person to begin with so I find it a much more suited drug to my personality than is piribedil, which had precisely the proadrenergic effect I need to suppress and stamp down so hard upon using clonidine and zanaflex/tizanidine. Goddamn though the stuff is pervy. I wasn't joking about that dog, either. Wish I could remember the name of the model and her dog actually. Had I been female, and not far more a cat person or invertebrate person with regards to pets then....no..really fucking hell these drugs are ones that take a little getting use to, they should be ramped up over a short-medium term to prevent overactivation of the chemoreceptor trigger zone, these drugs are capable of causing a pukefest. But piribedil was even somewhat of a sedative when the adrenergic autoreceptor issue for me was taken out of play inasfar as possible although far more activating than pramipexole.
With regards to its sexual stimulant effects it should be noted that in this stimulatory modality, it is made manifest in the manner that it facilitates, but does not force sexual activity At least in this subject it does act thus. It takes some getting used to. Attempting to ramp up the dose of these dopamine agonists too rapidly results in nausea and potentially vomiting. Can cause one major pukefest, And with orthosteric dopamine agonists at D2, is this not the autoreceptor? have always been a little unsure on the matter of D2 autoreceptors and especially the seemingly contradictory effects of neuroleptics.
