PitheGreek
Greenlighter
- Joined
- Nov 8, 2009
- Messages
- 7
What do you think is a good dose of baclofen for a mild anxyolytic, euphoric effect?
My doctor has had me on a high dose of neurontin for some time, but it does NOTHING for my anxiety. I beg him to put me on a benzodiazepine, but he refuses. My life is unmanageable with my anxiety/panic. He just wrote me a script for Baclofen, and says it might help. I can't find much information on this stuff at all. Does anyone knows anything about Baclofen?! Its supposedly a GABA-B agonist.
SWIM is on 12 mg's of suboxone daily and was prescribed one hundred and twenty 10 mg baclofen. The first two times SWIM took around 70mg's but didn't really know what to think about it, just felt weird and out of it and very clumsy and tired the next day. SWIM waited about a week to try this again because of all the positive and recreational effects SWIM's read about, and this time felt absolutely amazing. Very euphoric and SWIM has never tried GHB but could imagine it's very similar. SWIM had alot of energy and was very motivated. Also would doze off randomly and then randomly would have bursts of euphoric energy.. Absolutely had no anxiety and SWIM would think it's like a mix of Valium and GHB. Definitely euphoric and really looking forward to doing again. SWIM has also noticed that a dose of 60 mg's works perfect everytime and no tolerance has set in. This is also my very first post on bluelight so I apogize if this carried on too much or if I broke any bluelight rules.
Hi , I'm a neuropsych meself, doesn't mean I don enjoy pot, or never tried heroin , but I now mostly enjoy pharma cocktails:D lets talk of baclofen
Try Baclofen if u wanna feel good , its a GABA-B selective agonist - that'll relax muscle spasms due to injury, but gaba-b agonism DISINHIBITS AND SLOWLY SPEEDS UP DOPAMINERGIC transmission in pleasure centres of the brain. also seroternergic neurotransmission speeds up via indirect action on 5HT1A receptors and a happy relaxed state arises the higher u dose. BUT PLEASE DON GO ABOVE 75-100 mg and that's all this doctor can remember from the fat books I read long ago. A VERY DOPAMINERGIC COMBO IS MODAFNIL(200-300mg) + BACLOFEN(25-75mg) another is BACLOFEN(25-50mg)+MEMANTINE(10-20mg)+PRAMIPEXOLE(1-3mg) or a cocktail of RITALIN/BUPROPION(300-450mg) + EFFEXOR (150-225mg )+ BACLOFEN (50mg)IF U WANNA BLUES TRY PREGABALIN (900-1200mg) +VALIUM(20mg)+BACLOFEN(25-50mg)+XANAX1mg - take a shower, watch TV, chill out -BTW for u'r anxiety try escitalopram (lexapro 10)for 21 days though within 3 days u'll feel it, or paxil cr 25 these 2 SSRI act very fast, as does remeron start from a low dose or Desyrel from 25mg at bedtime-if u can get any of these from friends or anyone and give them atleast 21 days trial I'm sure u won't need a benzo,(though if u had come to me I would have started on Xanax 1mg or Klonopin 0.5mg) u can sedate with a tricyclic like Elavil 25
Uhh, no; baclofen has no direct activity at mu-opioid receptors (or ANY opioid receptors for that matter).. its main action is as a GABA-B agonist.psychihelp said:Suboxone cancels any opiod joy from baclofen
Uhh, wrong. Strike two.. GHB is a GABA-B agonist.psychihelp said:then GHB binds to GABA-A site
HAA! ..I was thinking exactly the same thing in regards to psychihelp. Apparently his "med schooling" didn't include grammar lessons? Doesn't even know the difference between GABA sub receptors & apparently thinks baclofen has opioidergic activity? So if he actually is a doc.. one, I pray to god (even though i'm an atheist) i never have him; and two, he should demand a tuition-refund from whatever shit school he supposedly went to.Tripman said:If this guy is a neuropsych then i'm a fish.