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Any videos out there of the head-twitch response/mice on LSD?

AA357

Bluelighter
Joined
Jul 19, 2014
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Apparently activation of the 5HT2A receptor causes a rapid side-to-side head movement in mice and rats. It's known as the 'head-twitch response' and is most often associated with psychedelic drugs:
http://en.wikipedia.org/wiki/Head-twitch_response

Bit of a random question but where can I find a video of this? I'm really curious to see what it looks like. I worked with mice for a while a few years back, plus I took some 2C-E earlier on this evening so the idea of mice on psychedelic drugs seems totally ridiculous.
 
The head twitch made by mice doesn't show up very clearly on standard video. They move their heads side to side a few times, but the entire sequence of movements takes only 50-100 msec. So you can tell that the head moved but can't make out what the mice are actually doing.

You can find high speed videos of wet dog shakes online and the mice pretty much look the same way on high speed video when they make a head twitch, except they don't move their body as much as the dogs do.
 
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