don't use high dosages frequently it is neurotoxic and wrecks your physics. any daily dosing regimen has toll on body that can be for great part to be perceived as stress. So it is not really that toxic to organs and not seriously damaging to nervous system on doses 5-50 milligrams (pharma level stuff) but it is not necessarily good or healthy either. Those doses are used in treatment of ADHD/ADD somewhat succesfully but some medicinal or non-medicinal users using those doses find acute and lingering side effects still remarkable. So even reasonable dosing and having break days requires listening to your body and psyche.
Some people find it very addictive and that can lead to very dark place very fast. Deluded, obsessed state with no interest to harm reduction practices. "Everything is just nicer little high on amphetamine" is dangerous thought, while true, until it is not true anymore. By ADHD/ADD medicinal users it tho' sometimes prevents development of substance abuse disorders.
There are no serious withdrawals upon cessation, commonly just fatique, depression, anxiety and hypersomnia. Dysfunctional but pretty well tolerated stuff.
Antioxidants, electrolytes, water and magnesium are great acute harm reduction. You should also be able to keep up with calorie intake and other nutrients high or at some point after the high or it won't really make you any more energized in the long run.
