here is yet another report from a low post count'er, because as stated before the site where i would have rather posted this to does not allow this kind of discussion.
most of this post i will be copying and pasting from another forum and from private correspondence with a friend. the pm's posted are only my own writing.
tested with marquis reagent, i only had that available. gave a clear yellow fizzing reaction, just like methylone. took a 7mg allergy dose, waited 4-5hrs, and insnufflated 166mg. i had read reports of oral use being more effective, and higher doses being required, but nasal was my favorite ROA with both m1 and 4-mmc, so for the sake of comparison i went the nasal route. i decided to keep the dose low because it was such a new compound. the effects came on more slowly and with much less rush than m1 or 4-mmc. i vomited when i hit my peak, but i wouldnt be to concerned about that, as i am prone to vomiting with alot of drugs, and have vomited from good quality 4-mmc while friends i gave the same dose to did not. at that point the effects seemed to fade slightly, and i insufflated another 65mg. the drips from this drug were awful, pain like 4-mmc but longer lasting, and with a significant long lasting burn. i dont think this material is going to be very healthy to insufflate. effects lasted 2-3 hrs, and while the tactile sensation was about on par with m1, i found the euphoria to be lacking. good, but lacking. this test run became botched however, as i was toying with making an vinyl hose attachment for my n2o dispenser, and broke it, repaired it, and sent 2 cartridges thru the dispenser to test if i had repaired it correctly, and once i did that whippet, the euphoria bottomed out until i did more, and more, etc...im sure n2o users have experienced this with other drugs.
my second trial began with 260mg oral, and 50mg nasal upon coming up from the oral dose. with a higher oral dose, and not using n2o, the euphoria was much better. i still found the tactile sensation to be the same as methylone, but the "magic" and euphoria to be lesser. its kind of a neat trick for commercial vendors...on the outside the product mimics methylone very well...but just as psychedelic users find with mescaline or LSD vs. RC's...the magic just isnt there. there was a slight visual aspect, but not much. everything was brighter, mildly defined, and i also had a mild sense of "awe and wonder" i get from true psychedelics like LSD or 2c-x.
starting about 1-1.5hrs after the 5ME kicked in, the strong urge to redose began. the amount i ingested was the whole rest of the bag so i could not redose, but the desire was clearly there. the high was better without taking the n20 beforehand, and i was able to enjoy it without just wanting whippets, but after a bit of time passed, the "falling off the cliff" feeling started, and was about the same as i experience with M1.
honestly with 2 uses i can say i find 5ME to have the least desirable comedown out of 5ME, 4-MMC, and M1. now for the ambiguity, i seem to have the opposite reaction to 4-MMC and M1 that alot of folks get...with 4-MMC i have no urge to redose, no crash, no comedown, i just drift peacefully to sleep and wake up the next day feeling as though i had a cup of tea and went to bed early the night before, not stayed up for hours on a cathinone. i actually find M1 much more compulsive than 4-MMC, and oftentimes ive redosed to the point of being worried about the dose getting to high(im very careful, a dose that worries me is likely commonplace for many cathinone users fwiw), and will continue to use M1 and nitrous until the M1 stops producing euphoric effects and im out of n20. i also notice more of a space out, and mental after effects(never had depression, just spacy, "cracked out") the next day with m1 than with 4-MMC.
so i dont get what others have been stating as minimal after effects, no desire to redose, but then again i do not experience this effect with 4-mmc, and seem to experience it more than most with methylone. but none-the-less after about an hour and a half i did experience a significant drop in euphoria, general blah feeling, and desire for more.
another interesting, and disappointing item to note is that i had alot of trouble sleeping. i usually pass out right when i hit the pillow when sober, it takes 30min to an hr when im on LSD or mescaline, and with empathogens, after any initial stimulation has worn off, i can usually get to sleep in 20-30min. with the 5ME it took a good 1-2hrs to fall asleep, and when i did, i slept very lightly, to the point where i was almost still slightly conscious, and woke up 3 or 4 times during the 7 hours i slept, however while sober i do not wake up, ever. being a cannabis smoker allows me to have no sleep problems whatsoever.
over 12 hours after ingestion i am still experiencing a rapid heart rate, and a "small penis", indicative of vasocontriction. i dont remember if 4-mmc or methylone producing rapid heart rate or vasoconstriction into the next day, but it has been some time since i tried either, and i could just not be remembering correctly. also experiencing more stiffness and tension the next day than i would with methylone or 4-mmc.
5ME is much higher cost than methylone or 4-mmc as well, even at my 300mg dose i would have perhaps liked 400mg. i should have eaten the whole 300mg, but was concerned about overloading with a new substance...compared to all other empathogens ive used 300mg seems high for a starting dose. the vendor of this compound recommends 500mg for m1 like effect and touts it as amazing, and to me it sort of seems absurd...yeah, duh! no one is getting exited over something like butylone as having magical m1 like effect, but im sure if you necked 500mg at once you'd be feeling damn fantastic!!!
the vendor is claiming its price is fair because it is only a few dollars for a few hours of great effects, and i see killermunchies here claiming it is alot cheaper than mdma, but honestly, if 4-500mg is a full, strong dose, which according to my trials, it will be for me @ least, it costs $10-$12 for a full dose, which IME is the same as "molly", powdered mdma, claimed to be of reasonable purity. i just got 4-EMC that will cost $1.5-$2 per strong dose. actual m1 could be had @ under $5 per strong dose. so compared to all other compounds with similar structure, it simply costs more. hell, my 25i-nbome costs about $.25-.50 per strong dose, that usually lasts a good 8-10 hours, and although totally different and tough to compare, the effects are alot more engaging than 5ME. compared to pretty much all other RC's, its not cheap for a few hours of great(great being a subjective quote, IME it is simply good) effects.
all in all i dont see any reason to use this over M1, even taking into consideration legal status and difficulty obtaining it. it just does not seem to have any advantages over m1, but rather several strong disadvantages, such as cost, the others mostly relating to the history of use and safety profile of M1 vs. the unknown nature of 5ME.